Annals of Vascular Diseases (AVD) is an international, peer-reviewed, open access journal publishing articles on vascular disease. Published continuously online, the journal is fully indexed in J-STAGE and PubMed Central. AVD welcomes submissions from around the world.
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The licensing policy for our journal has been updated. Starting from January 1, 2025, newly published articles will generally be licensed under the CC BY (Attribution) license.
– Articles published on or after January 1, 2025: Licensed under CC BY (Attribution).
– Articles published before January 1, 2025: Retain their original license, CC BY-NC-SA (Attribution-NonCommercial-ShareAlike).
– Secondary publications (e.g., translations) may follow the licensing terms of the primary publication.
For more details, please refer to the “Copyright, Open Access and Fees” section of the Instructions to Authors.
About the journal
AVD is an official journal of Asian Society for Vascular Surgery (ASVS) and Asian Venous Forum, sponsored by Japanese College of Angiology, Japanese Society for Vascular Surgery and the Japanese Society of Phlebology.
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Editorial Committee of Annals of Vascular Diseases
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Latest articles
Original ArticleMarch 11, 2026
Association between Changes in Stent Graft Volume and Type II Endoleaks after Endovascular Aneurysm Repair
Satoshi Yamamoto, Takuya Hashimoto, Takashi Endo, Masaya Sano, Osamu Sato, Juno Deguchi
Objectives: Type II endoleaks (T2ELs) after endovascular aneurysm repair (EVAR) are associated with delayed adverse events. This study evaluated the association between changes in stent graft volume (SgV) and T2EL after EVAR.
Methods: This study included 127 patients who underwent EVAR for abdominal aortic aneurysms between 2010 and 2022. SgVs were calculated using computed tomography, and SgV ratios were calculated by dividing SgV 2 years after EVAR by SgV immediately after EVAR. The association between the SgV ratio and T2EL 2 years after EVAR was evaluated.
Results: T2ELs were detected in 62 patients (49%) 2 years after EVAR. Univariate analysis revealed that age, number of patent lumbar arteries, expanded polytetrafluoroethylene (ePTFE) stent grafts, and the SgV ratio were significantly correlated with T2EL. Multivariate analysis showed that age ≥80 years, patent lumbar arteries ≥4, ePTFE stent graft, and SgV ratio ≤1.23 were independently associated with T2EL. In both the ePTFE (80 patients) and polyester (47 patients) stent graft groups, the SgV ratio was independently associated with T2EL.
Conclusions: The SgV ratio was significantly correlated with T2EL and may improve T2EL surveillance after EVAR.
Case ReportMarch 3, 2026
Successful Surgical Treatment for Large Common Hepatic Arterial Aneurysm Incidentally Discovered during Evaluation for Mallory–Weiss Syndrome
Daichi Mizushima, Tsutomu Doita, Sayaka Yuzawa, Takayuki Uramoto, Naoya Kuriyama, Yuri Yoshida, Atsuhiro Koya, Mishie Tanino, Shinsuke Kikuchi , Nobuyoshi Azuma
Although both open and endovascular repair are available for hepatic artery aneurysms (HAAs), the optimal treatment strategy remains controversial, particularly in anatomically complex cases. In the present case, a large common HAA measuring 100 × 49 mm with a short proximal neck posed significant challenges for both modalities. To ensure intraoperative hemostasis, a hybrid approach was adopted: open surgical ligation combined with prophylactic balloon occlusion at the aneurysmal neck. This strategy enabled safe exclusion of the aneurysm without hepatic ischemia. The case underscores the importance of selecting open, endovascular, or hybrid techniques based on individual anatomical complexity to optimize outcomes in HAA management.
Case ReportMarch 3, 2026
Endovascular Repair of Thoracoabdominal Aortic Aneurysm under Locoregional Anesthesia
Kenichi Kato, Tsuyoshi Shibata, Yutaka Iba, Tomohiro Nakajima, Junji Nakazawa, Ayaka Arihara, Shigeki Komatsu, Masato Yonemori
An 80-year-old female presented with a thoracoabdominal aortic aneurysm (TAAA) that had progressively enlarged to a diameter of 58 mm. She was scheduled for TAAA repair; however, she had a severe obstructive ventilatory disorder, which posed significant risks. Both open repair and general anesthesia were deemed to carry a high risk of respiratory complications. Consequently, an endovascular TAAA repair was performed using a physician-modified inner-branched endograft under locoregional anesthesia. This approach successfully treated the TAAA without any major complications. This strategy opens up the possibility of treating TAAA in patients with severe comorbidities that were previously challenging to treat.
Case ReportMarch 1, 2026
Thoracic Aortic Aneurysm Following Blunt Trauma in a Patient with a Monoallelic SLC2A10 Variant: A Case Report
Satoshi Uesugi, Naoyuki Kimura, Shogo Saito, Mamoru Arakawa, Arata Muraoka, Yasushi Imai, Koji Kawahito
A female in her early 40s with no skeletal abnormalities was incidentally found to have a 45-mm saccular aneurysm at the aortic isthmus during evaluation for pharyngitis. She had sustained blunt trauma 20 years earlier, resulting in multiple fractures and pneumothorax. Her family history included premature vascular or sudden death and scoliosis. Imaging showed no arterial tortuosity. She underwent successful open surgical repair. Histologic examination revealed disorganized elastic fibers with irregular thickening and partial loss of lamellar architecture. Postoperative genetic testing identified a heterozygous missense variant in SLC2A10, suggesting a possible association between monoallelic variants and vascular fragility.
Case ReportMarch 1, 2026
A Fatal Case of Acute Pulmonary Embolism after Cyanoacrylate Closure for Varicose Veins
Kenichi Chatani, Hiroyuki Ihori, Kazumasa Ohara, Makoto Nonomura, Tomoki Kameyama, Hiroshi Inoue
An 81-year-old female with bilateral small saphenous vein varicosities (CEAP, C2s, Ep, As, Pr) underwent cyanoacrylate closure (CAC) and stab avulsion under general anesthesia. Fourteen days later, she developed severe dyspnea and was diagnosed with pulmonary embolism (PE) and deep vein thrombosis. Despite anticoagulation, cardiopulmonary support, and catheter-directed thrombectomy, she died 24 days after admission. Adequate heparin dosing with activated partial thromboplastin time monitoring is important. Prolonged procedures under general anesthesia may increase PE risk. Early ambulation, compression therapy, and follow-up ultrasonography beyond 24 hours may help detect delayed thrombus formation and reduce life-threatening complications after CAC.
Case ReportFebruary 26, 2026
Distal Radial Artery Aneurysm of the Dorsal Branch with Ulnar Artery Occlusion: A Case Report
Yoshihiko Onishi, Akihiro Sasahara, Saya Ishikawa, Kenjiro Sakaki, Ko Shibata, Masaki Nie, Kuniyoshi Ohara
We report a rare case of a radial artery aneurysm associated with ulnar artery occlusion in an 80-year-old female. Preoperative imaging showed poor visualization of the palmar arch and absent ulnar flow, prompting aneurysmectomy and radial artery reconstruction using a vein graft. Intraoperative findings revealed good retrograde flow, suggesting preserved distal perfusion. This case highlights the importance of accurate preoperative assessment of hand arterial anatomy, particularly the palmar arch, in determining the need for revascularization in radial artery aneurysms with compromised collateral circulation.
Featured articles
GuidelineJune 6, 2025
Supplement of Clinical Practice Guidelines for Endovenous Thermal Ablation for Varicose Veins 2019: Laser Ablation of Varicose Tributaries
Masayuki Hirokawa, Junichi Utoh, Satoru Sugiyama, Osamu Suzuki, Takashi Yamamoto, Tomohiro Ogawa, Makoto Mo, on behalf of the Guideline Committee, Japanese Society of Phlebology
In the treatment of saphenous varicose veins with endovenous laser ablation, simultaneous treatment of varicose tributaries using stab avulsion or sclerotherapy is commonly performed. To address the limitations of these conventional treatments, laser ablation for varicose tributaries has recently gained widespread acceptance. This guideline, developed by the Japanese Society of Phlebology, outlines appropriate treatment protocols for laser ablation of varicose tributaries. Indications include primary varicose veins requiring concurrent treatment of the saphenous trunk and varicose tributaries. The procedure utilizes slim radial fibers, with puncture and ablation performed using either short- or long-axis approaches. Although rare, adverse events such as skin burns, nerve injury, and fiber breakage have been reported. A learning curve is necessary to ensure the safe execution of the procedure. Further clinical studies are essential to enhance the safety and efficacy of laser ablation for varicose tributaries. (This is a secondary publication from Jpn J Phlebol 2025; 36: 51–58.)
Overview of type 2 endoleak following endovascular aneurysm repairMarch 25, 2023
Surgical Treatment of Sac Enlargement Due to Type II Endoleaks Following Endovascular Aneurysm Repair
Seiji Onitsuka, Hiroyuki Ito
An aneurysm sac enlargement caused by type II endoleak (T2EL) following endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms may cause serious complications such as rupture. Consequently, methods that preoperatively prevent or postoperatively treat T2EL have been employed.
Therapeutic Angiogenes UpdateDecember 25, 2022
Therapeutic Angiogenesis Using Autologous CD34-Positive Cells for Vascular Diseases
Yasuyuki Fujita, Atsuhiko Kawamoto
CD34 is a cell surface marker, which is expressed in various somatic stem/progenitor cells such as bone marrow (BM)-derived hematopoietic stem cells and endothelial progenitor cells (EPCs), skeletal muscle satellite cells, epithelial hair follicle stem cells, and adipose tissue mesenchymal stem cells. CD34+ cells in BM and peripheral blood are known as a rich source of EPCs.
Updates on Image Diagnosis in Aortic DiseaseDecember 25, 2018
Update on Cardiovascular Echo in Aortic Aneurysm and Dissection
Kazuhiro Nishigami
The majority of aortic aneurysms comorbid with atherosclerosis can be asymptomatic and are discovered incidentally on routine physical examination or on imaging studies for other indications. Transthoracic echocardiography is a basic modality to assess patients with coronary artery disease and can be used for the screening of aortic aneurysm. Acute aortic dissection is a highly lethal cardiovascular emergency and requires prompt recognition. Although cardiovascular echo has a suboptimal accuracy rate for detecting aortic dissection, it is noninvasive, readily available, and easy to use. Recently, the concept of point-of-care ultrasound (POCUS) refers to ...
Updates on Image Diagnosis in Aortic DiseaseSeptember 25, 2019
Updates on Ultrasonography Imaging in Abdominal Aortic Aneurysm
Shinichi Iwakoshi, Toshiko Hirai, Kimihiko Kichikawa
Abdominal aortic aneurysms (AAAs) are life-threatening and are associated with >80% mortality when they rupture. Therefore, detecting these aneurysms before they rupture is critical. Ultrasonography is a non-invasive tool that is used for screening AAAs by measuring abdominal aorta diameter. A recent meta-analysis demonstrated the positive effects of ultrasonography. To date, aneurysm diameter is the most reliable predictor for aneurysm rupture and is used as a criterion for surgical intervention. However, some AAAs rupture at small diameters. Therefore, a better predictor for AAA rupture that is independent of aneurysm diameter is needed. Recently, an aortic wall strain examined using ultrasonography has been reported to have a potential in predicting AAA rupture....
Updates on Image Diagnosis in Aortic DiseaseMarch 25, 2020
Updates on Computed Tomography Imaging in Aortic Aneurysms and Dissection
Ryoichi Tanaka, Kunihiro Yoshioka, Akihiko Abiko
Computed tomography (CT) is a primary imaging modality for the diagnosis of aortic diseases, because of its minimal invasiveness and agility. Prompt and accurate diagnosis is crucial especially for acute aortic diseases, and the guidelines for acute aortic dissection recommend the use of CT for initial diagnosis. For the follow-up observation of longstanding aortic diseases, the strategy of imaging management by CT must be different from that for emergency and acute phases. In this review, we document the differences in characteristics and clinical course between aortic aneurysm and aortic dissection and explain the use of recent CT techniques in diagnosing short- and longstanding aortic diseases.